25 replies to this topic

[Kate]

EDIT: The latest version of my list is always here, I can't always keep forums up to date - http://vapersnetwork.org/node/8



A compilation of studies related to vaping.



SuperSmoker eliquid toxicology report - http://www.supersmokerjp.com/images/Toxi...atiion.pdf


The Electronic Cigarette Co eliquid toxicology report - http://www.tobaccoha...on.org/tox1.pdf


Gamucci eliquid toxicology report - http://www.ecigarett...cciLabStudy.pdf


EcoPure report - http://www.intellicig.com/images/pdf/ECO...-04-14.pdf


Spikey's collection of research about propylene glycol - http://www.vapersclub.com/pg.html


Spikey's collection on Studies showing simple rebuttal to FDA report - http://vapersclub.com/safe.html


Ruyan, NRT effectiveness - http://www.healthnz....ig_effect-2.pdf


Ruyan, eliquid analysis - http://www.healthnz.co.nz/RuyanCartridge...Oct-08.pdf


Ruyan, summary of research - http://www.healthnz....htopHandout.pdf


E-cig study for metals - http://acceptablecho...GeneralView.htm


Toxicology report on pvliquid from e-cigs.co.uk - http://www.e-cigs.co.uk/docs/E249A.pdf


Research that suggests no long-term harm from nicotine inhalation - http://www.ncbi.nlm..../pubmed/8614291


A report on Johnson Creek pvlliquid - http://www.johnsoncreeksmokejuice.com/do...Report.pdf

Edited by Kate, 14 February 2010 - 04:02 PM.

[Jackie]

Very useful post, thanks, and stickied. :)

[westcoast2]

A link to Carl V. Phillips and Brad Rodu site on Tobacco Harm Reduction. This puts some of the studies into context, gives info on the e-cig and discusses nicotine. It is slanted towards ST (Smokeless tobacco) but does provide ways to balance the 'quit or die' ant-smoking (anti-nicotine) groups in a simple and straightforward way.

--> http://www.tobaccoha...rg/faq/menu.htm

[Toby]

Rob (AltSmoke) emailed me this yesterday....

Doesn't this seem to contradict what's in the copyright pdf that you have Jackie?

I'm a bit confused about it all (and also not sure where to post, so please feel free to move it...)

"In contrast to claims made in the CNN article (below), Tom Eissenberg's new study (attached) found that two e-cigarette products (marketed by NJOY and Crown Seven) delivered nicotine to users at levels similar to various low-nitrosamine smokeless tobacco products and nicotine gums, lozenges and patches.
The study also found that, as with cigarette smoking, plasma nicotine levels peak quickly (about five minutes) after e-cigarette usage, unlike oral and transdermal tobacco/nicotine products that take far longer to peak. Smokers in the study, all of which were first time e-cigarette users, also reported that e-cigarettes reduced cigarette/nicotine cravings.

Five minutes after use, mean plasma nicotine levels of users increased to 3.0-3.4 ng/ml for the NJOY e-cigarette, and to 2.5ng/ml for the Crown Seven e-cigarette. Fifteen minutes after use, mean plasma nicotine levels of users had declined to 2.8-3.1 ng/ml for the NJOY e-cigarette, and to 2.3 ng/ml for the Crown Seven e-cigarette. Thirty minutes after use, mean plasma nicotine levels of users had declined to 2.6-2.9 ng/ml for the NJOY e-cigarette, and to 2.2-2.3 ng/ml for the Crown Seven e-cigarette.

For comparison, a previous study by Eissenberg at http://static.mgnetw...090712_toba.pdf found mean plasma nicotine levels fifteen minutes after product use at 2.9 ng/ml for Altria's Marlboro Snus, 3.4 ng/ml for Star's Ariva tobacco lozenge, 4.6 ng/ml for GlaxoSmithKline's 2mg Commit nicotine lozenge, and 7.6 ng/ml for RJ Reynolds' Camel Snus, all of which were significantly higher than levels five minutes after product use. Other studies (1,2) have similarly found plasma nicotine levels peaking at fifteen, thirty or sixty minutes following usage of smokefree oral tobacco/nicotine products ranging from 2-7 ng/ml for Star's Ariva and Stonewall tobacco lozenges, UST's Revel snus, GSK's 2mg Commit nicotine lozenge, and 2mg nicotine gums, while UST's Copenhagen moist snuff and Swedish snus can increase plasma nicotine levels to 10-16 ng/ml. Meanwhile, cigarettes increase plasma nicotine levels to 15-25 ng/ml within five minutes after usage, which declines rapidly thereafter.
(1) Nicotine pharmacokinetics and subjective effects of three potential reduced exposure products, moist snuff and nicotine lozenge, M Kotlyar, MI Mendoza-Baumgart, ZZ Li, PR Pentel, BC Barnett RM Feuer, EA Smith, DK Hatsukami, Tob Control 2007;16:138-142. http://tobaccocontro...t/16/2/138.full
(2) Effect of smokeless tobacco (snus) on smoking and public health in Sweden, J Foulds, L Ramstrom, M Burke, K Fagerström Tob Control 2003;12:349-359. http://tobaccocontro...t/12/4/349.full

The comments posted on CNN's webpage (weblink below) by many e-cigarette users also reveal far more objective information about e-cigarettes than does the CNN article."

http://www.cnn.com/2...ette/index.html

and a related thread -
http://www.e-cigaret...-com-today.html

Edited by Toby, 14 February 2010 - 03:48 PM.
added links

[Jackie]

All I know is that there's no way I'm getting a placebo effect. I know immediately if I've accidentally picked up a 0mg cart from a new kit for example (I usually use 24mg).

Mind you even if it were a placebo effect I wouldn't really care, the main thing to me is that it works and I enjoy it. :)

It does seem very contradictory though, yes.

[Kate]

Dr Tom can't make his mind up if we're getting nicotine or not:

Quote

... Eissenberg said he's concerned about comments he has seen on blogs that some e-cigarette users are "dripping," or letting liquid from the devices' cartridges fall directly onto the heating element.

That means they may be getting relatively large doses of nicotine, which can be toxic in amounts of about 50 milligrams, Eissenberg said...

http://www2.timesdis...-215209/323735/

[Ochso Kube]

Dont know if this should go here or not..

Please feel free to move it.

[Onceupon]

westcoast2 said:

--> http://www.tobaccoha...rg/faq/menu.htm

http://www.tobaccoha...apers/press.htm

Sorry if this link has been posted before.

For the average smoker, the study finds, smoking for just one more month poses a greater health risk than a lifetime of using...the new electronic imitation cigarettes...

[Kate]

Would one of you kind souls nip over to ECF and attach that study to this forum or send it to me pretty please? I can't see it because I can't log in.

New Eissenberg study vindicates e-cigarettes
http://www.e-cigaret...cigarettes.html

Ta x

[hifistud]

Vansickel 2010 E-cigarettes clinical.pdf

That one??

Seems little different to the first one he did...

[Kate]

That looks like the one, thanks very much Dave.

[Kate]

Oh, I've just tried to open it, it's still the link to ECF and I can't sign in. Please could someone attach it here for me?

thanks.

[hifistud]

I'll try again - it's the final report of the original study - aside from a more careful choice of words, nothing's changed in it.

Attached....

Attached Files

•  Vansickel 2010 E-cigarettes clinical.pdf   228.67K   11 downloads

Edited by SubVap, 23 July 2010 - 08:22 PM.

[Kate]

I was wondering if it was a new one, I'd have thought there would have been some fuss about the research being commissioned. I also wondered why Eissenberg would do two studies that are of the same thing.

This is the original report if you're interested:

 EissenbergFINAL e-cig PDF.pdf   122.97K   6 downloads

[deewal]

Kate, on 23 July 2010 - 08:36 PM, said:

I was wondering if it was a new one, I'd have thought there would have been some fuss about the research being commissioned. I also wondered why Eissenberg would do two studies that are of the same thing.

This is the original report if you're interested:

EissenbergFINAL e-cig PDF.pdf

Bill Godshall who posted it say's "The results vindicate e-cigarettes."
Right then. Send it to the MHRA.

[Kate]

Bill Godshall is a goody but he's a bit of a divvy, Dee. He was all over the UK Dept of Health the day they brought out their Smokefree consultation report because they claimed to support harm reduction. The fact that they were going to ban it at the same time went right past him. He's also been encouraging US vapers to campaign for tobacco regulation and I have a very bad feeling that's going to be one of the worst moves they could possibly take.

Anyway, Eissenberg's research is handy because it shows that ecigs don't do anything much useful that can be claimed to change physiological functioning and that's what the MHRA are using as their argument to close the market. It's probably best for us if researchers prove that ecigs aren't an effective medicine. I've already told the MHRA all about Eissenberg's research - not that they've probably read it or care.

[westcoast2]

Haven't got the study page but here's a report on e-cigs and suction from UC Riverside (CA) --> Electronic Cigarettes Require More Suction Than Conventional Brands

There is much wrong with this 'study'

[VaporCloud]

westcoast2, on 28 July 2010 - 08:13 PM, said:

Haven't got the study page but here's a report on e-cigs and suction from UC Riverside (CA) --> Electronic Cigarettes Require More Suction Than Conventional Brands

There is much wrong with this 'study'

Baffles me how such misinformed rubbish such as that study can be posted on the internet as fact. Sucking on an ecig actually produces much less vapour than just lightly drawing on one!

[XPaulC]

Long-term effects of inhaled nicotine - http://www.ncbi.nlm..../pubmed/8614291

- In conclusion, our study does not indicate any harmful effect of nicotine when given in its pure form by inhalation.

I had read this before in other places, but this was a 2 year study, so they say...

[googled]

http://www.engadget....l-ones-no-ciga/

http://sph.bu.edu/in...&articleid=3366

Edited by googled, 18 December 2010 - 02:13 PM.